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Thursday, November 06, 2008


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Pfizer Halts Obesity Drug on Risk of U.S. Rejection

Pfizer Inc., the world's largest drugmaker, said it will quit testing an obesity drug similar to ones junked by other companies because winning U.S. approval would be too slow, expensive and risky.

Pfizer is unwilling to pour money into new human tests the U.S. Food and Drug Administration is likely to require, the New York-based drugmaker said today in a statement. The drug, known by the chemical name CP-945,598, was in the third of three stages of testing required for market clearance and could have had more than $500 million in annual sales, analysts said.

Pfizer is among the last drugmakers to abandon obesity medicines that block the same brain receptor that makes marijuana smokers hungry. Before Sanofi-Aventis SA's drug was rejected by the FDA in June 2007 and Merck & Co. quit developing its version last month, analysts estimated annual sales of the products would top $3 billion.


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Monday, November 03, 2008


Hypnosis Basics

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Chantix Faces Further FDA Scrutiny

The Food and Drug Administration (FDA) may issue a revision of its warning on Pfizer's controversial smoking-cessation drug Chantix, the Wall Street Journal reported Oct. 23.

Just a few months after Pfizer relaunched television advertisements for the drug, the Institute for Safe Medication Practices released a report highlighting 1,001 recent, serious incidents involving Chantix. Of these, 15 were related to traffic accidents and 52 were connected to blackouts.

"The most alarming thing about the numbers is the increase in loss of consciousness like a blackout, and the sudden [temporary] loss of vision," said report co-author Curt Furberg, a professor at Wake Forest University's medical school. "That's potentially very dangerous for everyone, as the traffic-accident numbers show."

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